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Advantages of VacciGuard's Technology |
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VacciGuard's vaccine technology has the following advantages over the existing vaccine technologies:
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The conjugated vaccines act as natural/endogenous adjuvants. Therefore there is no need for an external adjuvant with its associated side-effects.
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The carriers, HSP-60-derived peptides, are relatively short and do not induce the production of neutralizing antibodies. Therefore, no "carrier-induced epitope suppression" phenomena are elicited. This contrasts with carriers such as the tetanus toxoid, cholera toxin or diphteria toxoid.
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HSP-60 derived peptides are universal T cell epitopes and therefore enhance the T cell function, supporting the generation of long-lasting memory (formation of IgG antibodies by B cells).
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The conjugated vaccines are relatively stable and easy to store.
| Vaccine Type |
Immunogenicity |
Adjuvant |
Safety |
Long-term Efficacy |
Storage, Stability |
| VacciGuard |
+++ |
Not needed |
+++ |
+++ |
+++ |
| Attenuated pathogens |
+++ |
Needed |
+ |
+++ |
+ |
| Subunits |
+ |
Needed |
+++ |
+ |
+++ |
| Conjugated subunits |
++ |
Needed |
++ |
++ |
+++ |
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